Study of pharmacokinetics and pharmacodynamics of Crocus sativus

Study of pharmacokinetics and pharmacodynamics of Crocus sativus

Study of pharmacokinetics and pharmacodynamics of Crocus sativus

Authors
Vishwanath Kaiwart
Published in
Vol 1, Issue 2, 2025

Abstract

Crocus sativus L. (saffron), widely cultivated in Iran, India, and Greece, is a medicinal plant with over 150 bioactive compounds, including picrocrocin and safranal, responsible for its bitter taste and aroma. It exhibits diverse pharmacological activities such as antihypertensive, anticonvulsant, antioxidant, antidepressant, anti-nociceptive, and anti-inflammatory effects, along with memory-enhancing and circulatory benefits. In this study, 30 cases were assessed using random sampling and detailed case histories. Results showed marked improvement in 20 patients (67%), no significant improvement in 6 (20%), and no improvement in 4 (13%). Findings suggest Crocus sativus has a promising scope as a homeopathic therapeutic remedy.